Mostly yes. It works for MT65xx, MT67xx, MT68xx, MT816x, MT876x, and newer Dimensity series (though Dimensity may require updated drivers).
To obtain it safely, avoid sketchy driver sites. Instead, download a trusted SP Flash Tool package or an official MediaTek driver bundle. Installation requires disabling driver signature enforcement on modern Windows versions and may involve a manual update via Device Manager.
No. VCOM drivers are Windows-specific. For macOS, use mtkclient with libusb.